منابع مشابه
Pegylated interferon fractal pharmacokinetics: individualized dosing for hepatitis C virus
24 Background : Despite recent advances in hepatitis C virus (HCV) therapeutics, the combination 25 of pegylated interferon (PEGIFN) and ribavirin (RBV) remains the cornerstone of treatment. 26 Optimization and individualization of PEGIFN dosing could improve outcomes. 27 Methods: Week one PEGIFN serum concentrations in 42 HCV genotype 1 infected patients 28 treated with conventional PEGIFN/RBV...
متن کاملPegylated interferon-alfa plus ribavirin therapies for chronic hepatitis C.
Until HCV NS3/4A protease inhibitors become available at the end of 2011, the combination pegylated-interferon (PEG-IFN)-alfa and ribavirin (RBV) will remain the standard treatment for chronic hepatitis C patients. In some hepatitis C virus-infected patients, PEG-IFN plus RBV treatment against HCV should continue to be used because of side effects of new drugs such as anemia. Our Japanese exper...
متن کاملPegylated Interferon and Ribavirin Treatment for Hepatitis C Virus Infection
1Department of Gastroenterology, Tokai University School of Medicine, 143 Shimokasuya, Isehara 259-1193, Japan 2Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical Center, Palo Alto, CA 94304-1509, USA 3Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung...
متن کاملAcute Exacerbation of Liver Disease Induced by Pegylated Interferon Alpha2a Treatment for Chronic Hepatitis C
A 66-year-old female was referred to a local clinic for the treatment of chronic hepatitis C. Her family physician started the administration of Peg-IFN alpha2a in combination with ribavirin in September, 2008. Three months after the commencement of the therapy, alopecia was noted, and it gradually worsened. She also complained of general fatigue. Since her alopecia and general fatigue continue...
متن کاملSevere muscle weakness during treatment with pegylated interferon alfa for chronic hepatitis C virus infection A rare complication
Background: Interferons (IFNs) are common therapeutics for several diseases such as viral hepatitis, multiple sclerosis and malignancy. A variety of autoimmune related side effects have been observed during IFN therapy. Rare cases of myopathy, polymyositis or dermatomyositis have been reported during therapy with high doses of IFN^5. Case Presentation: In this report, we describe a case with se...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2019
ISSN: 1465-1858
DOI: 10.1002/14651858.cd006392.pub2